Polycystic Ovary Syndrome (PCOS)

Androgens in Preeclampsia

Question:

There was a discussion recently about preeclampsia and pco.  I thought you might all be interested to read this: Androgens in preeclampsia Michael T. Acromite, MDa [MEDLINE LOOKUP] Christos S. Mantzoros, MDb [MEDLINE LOOKUP] Richard E. Leach, MDc [MEDLINE LOOKUP] Janet Hurwitz, MAb [MEDLINE LOOKUP] Leonard G. Dorey, MDa [MEDLINE LOOKUP] Pontiac and Detroit, Michigan, and Boston, Massachusetts Objective: The purpose of the study was to determine whether maternal serum levels of androgens, especially testosterone, are higher in patients with preeclampsia than in matched normotensive control subjects. Study Design: Serum testosterone, dehydroepiandrosterone sulfate, sex hormone binding globulin, and estradiol levels were measured in 16 subjects in the third trimester of pregnancy with documented preeclampsia and 26 healthy, normotensive women with similar maternal and gestational ages. All subjects were primigravid women with singleton pregnancies who were seen in the labor and delivery department at North Oakland Medical Centers in Pontiac, Mich. Results: Total testosterone and free testosterone levels were significantly higher in patients with preeclampsia (213.6

Filed under: PCO

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