Polycystic Ovary Syndrome (PCOS)

Decreasing Dosage/Glucophage XR

Question:

Here is a new one to me… Today I went in to a new OB/GYN and discussed Glucophage for PCO, hoping that she’d see it my way and increase my dosage to 1500mg daily.  She told me that the REs and Endocrinologists she works with only use 500-1000mg daily (500mg being the usual dosage), and that even higher dosages may work against me in terms of losing weight due to the Met increasing the sensitivity of my insulin.  She said higher dosages will not help me lose weight, and will not help me ovulate, nor will it help excess hair growth (though I don’t battle this affliction).  She mentioned that Met does nothing for reducing androgens (I have elevated DHEAS and LH levels). She recommends that I go back to 500mg daily…that it may help me ovulate and I may actually lose weight again.  In retrospect, I did the best when I was on 500mg…I did gain weight when I went to 1000mg and I feel I haven’t ovulated on 1000mg.  I’m not saying she is right (there could be other reasons, of course)… She was pro Atkins (or other LC WOE) so I was happy at least about that. However, here I was thinking that since she is familiar with the use of Met for PCO, she’d increase my dosage.  Now she wants me back on 500mg!  Has anyone else been told this before? Chele

Response:

"Chele" <mar…@nospamchartermi.net> wrote in news:uuplk35uc4vj99@corp.supernews.com: > Here is a new one to me… > Today I went in to a new OB/GYN and discussed Glucophage for PCO, > hoping that she’d see it my way and increase my dosage to 1500mg > daily.  She told me that the REs and Endocrinologists she works > with only use 500-1000mg daily (500mg being the usual dosage), and > that even higher dosages may work against me in terms of losing > weight due to the Met increasing the sensitivity of my insulin.

I believe PCO studies have found 1500 to be the lowest effective dose. My endo had me go up to 2550 mg as quickly as the side effects allowed. — —->Sagittaria<—- "Some are born geeks; some become geeks through choice; and others have geekdom thrust upon them." -a character in an Orson Scott Card story

Response:

Filed under: PCO

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