Polycystic Ovary Syndrome (PCOS)

First time on pergonal

Question:

Hi!   This is the first time I have visited this site and I am about to start my first cycle of Pergonal.  I have had 7 cycles of Chlomid of which one worked.  I am PCO, and the one cycle that worked was with 200 mg Chlomid and .5mg dexamethazone to suppress the adrenal glands.   Anyone who has used pergonal please respond with how hard the procedures are. Specifically, I have for obvious reasons not told my work that I am trying and I think my boss is getting a little curious why I keep leaving for so many lunches away from the office.  I know pergonal will take even more time away than the follicle scans and chlomid follow-up.  The good thing is my insurance is covering pergonal so I don’t have very much expense. How are you doing the injections?  I travel a lot with work and so I’ll have to inject myself. Is this hard to do?  A general explanation would be great coming from someone who knows.  Thanks.

Response:

The one thing you need to do before you start the shots is to ask your doc for a prescription of EMLA cream. It’s a topical anesthetic, and it WORKS–in two weeks of giving myself the Pergonal shots, I only hurt myself once, and that was when I got too close to a nerve. Nerve was also my biggest problem–I knew it wasn’t going to hurt, but I couldn’t convince my hand! As far as the time goes, I gave myself the shots before bed each evening, and I had applied the EMLA about an hour and a half beforehand. The monitoring was done in my doc’s office every morning, but they opened at 7:30 and it only took about half an hour, so this wasn’t a big problem. You might want to check and see what hours your doc has–you really need to do this first thing in the morning so that they can call you back with your dosage in the afternoon. I have to agree with the comment already on here about Pergonal not necessrily being the drug of choice for PCO: Pergonal and it’s derivatives have additional LH that Metrodin, etc. does not, and I’ve always understood that those with PCO already had too MUCH Lh. You might want to ask your doc about this–is he/she an RE? Let me know if you have any other questions–Sue

Response:

Hi!  I have been on several cycles of Perganol and also have PCO.  I give the shots to myself.  The first time, it took me about 20 minutes to work up the nerve, but it gets easier  I think the anxiety is 100x’s worse than any pain you may feel from the needle!  I go to the doctors every morning from day 2 to ?  for blood work and every other day for ultrasounds.  Usually, it ends up being through day 18 or so.  Basically, it’s a very busy two weeks.   FYI :  After being on perganol, I switched to a doctor at a large fertility institute that told me that I never should have been on Perganol since i have PCO (of course, this may not be true in all PCO cases )  I would always hyperstimulate on Perganol and Humegon.  This doctors said that I need to be on a Clomid/ Metrodin combo.  The first month we tried it was the only cycle that I haven’t hyperstimulated.  While I didn’t get pregnant, it was only our first try on a regimen that  works…we start our second cycle tomorrow!  Good luck. Karen I Cor. 1:18

Response:

Filed under: PCO

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