Polycystic Ovary Syndrome (PCOS)

mini dose protocol

Question:

Hi Abby- My RE does a protocol somewhat similiar.  I am 33, have pco, have had 3 mc’s. Last cycle I took the bc pill for 3 weeks, on the 3rd week I tool .2cc of Lupron, got AF, then on day 3, 4 or 5 went in for a baseline u/s, started fertinex shots (1.5 amps but was eventually bumped up to 2 amps daily), and decreased the Lupron to .1 cc.  I have not done iui nor ivf. I must have had the longest cycle ever-31 days! LOL!  We are taking a month (at least) off and then decide what to do next.  My RE said we’d do the identical protocol on the next cycle. Best of luck to you! Wendy

Response:

<<My RE does a protocol somewhat similiar.  I am 33, have pco, have had 3 mc’s. Last cycle I took the bc pill for 3 weeks, on the 3rd week I tool .2cc of Lupron, got AF, then on day 3, 4 or 5 went in for a baseline u/s, started fertinex shots (1.5 amps but was eventually bumped up to 2 amps daily), and decreased the Lupron to .1 cc. Wendy, you are describing a typical downregulation protocol (not microdose, not minidose, not flare).  This is quite different than what Abby is doing.

Response:

Hi everyone. Again my my strong belief in using these newsgroups is validated. I posted a message on several newsgroups asking if anyone has been on a mini dose protocol and got a wonderful response. I am listing it here to just show how psoting your concerns can bring great relief. So here is my message with the answer.

<< Now my  re has me stopping the Lupron when I start the Gonal-f. Has anyone heard about this? I thought the Lupron helps prevent early ovulation so why is my re stopping it when I am doing Gonal-f? I have a phone call in to my nurse about it and I hope she gets back to me because I am starting the Gonal-f tonight. here is the response: I used Lupron for 10 days and once I was completely supressed, I started with Follistim and stopped the Lupron. My RE often uses this protocol, especially with woman like myself who are easily overly supressed . I did not have a premature LH surge and ended up with 18 mature follicles none of which were ovulated in advance of the retreival ( although it is scary once you have the HCG shot. I kept wondering if the eggs were still there and it was a very long thirty four hours. ) In the cycle before the one I described, I produced only 2 follicles due to my sensitivity to the Lupron and the IVF was converted to an IUI. The second cycle was successful and I am now 32 weeks pregnant, so be assured that what your RE ids doing can work, I would be happy to answer any questions you might have, just ask. Abby: Wasn’t this great? Before I was so nervous and scared my re was doing something wrong and now I am hopeful. What a day. hugs to all. Abby

Response:

Hi. has anyone heard of a mini dose protocol? My nurse told me that this is what I am on. I took Lupron from the 3rd week fo my cycle up until I start Gonal-f, 3 amps in the am and 3 amps in the pm. I stop taking the Lupron when on the gonal-f. Different eh? I asked the nurse to find out how early ovulation is prevented. She asked a doctor and they said that by taking the Lupron before the Gonal-f that it still helped to prevent early ovulation. That you didn’t need to take the Lupron at the same time as the Gonal-f. If anyone has done this protocol or has heard about it I would appreciate hearing about it. Thanks again for listening. Abby

Response:

Filed under: PCO

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