? about Gonal F
Question:
I have had several protocals of pergonal without sucess of a preg. The Dr. has mentioned changing to a protocal with Gonal F. If I was responding well with pergonal just not concieving what is the diffrence with Gonal F? Any higher conception rate? and does anyone know what dosage they start with? Thanks for any input. LC — Posted from [65.64.77.138] via Mailgate.ORG Server – http://www.Mailgate.ORG
Response:
<<what is the diffrence with Gonal F? Pergonal contains LH. Gonal-F doesn’t. Therein lies the difference. Briefly put, LH helps to promote egg maturation. However, eggs can become *too* mature in a given cycle. Gonal-F might give you slightly less mature eggs, which could be in your favor. Some RE’s use them interchangeably. My RE switched me from Fertinex (similar to Gonal-F) to Pergonal for no real reason, other than I wasn’t getting/staying pg with Fertinex, despite good ovulation and apparently good egg quality. He just figured Pergonal was worth a try (and it just so happened to work, too….clinical pregnancy, carried to term). 2 yrs later, I am presently 14 weeks pg from Gonal-F. In my situation, I don’t think Gonal-F was any better or worse, or more or less effective, than the Pergonal. (my sole cause of infertility is anovulation from PCOS). Other circumstances may vary. Might as well give the Gonal-F a try. Good luck, -Kay
Response:
Hi Kay, Just to be curious. I understand Pergonal is the same stuff as Menogon (FSH/LH combo). What was the dosage when you started. My RE had me started at one amp per day. Sophie, in Paris – Hide quoted text — Show quoted text – <<what is the diffrence with Gonal F? Pergonal contains LH. Gonal-F doesn’t. Therein lies the difference. Briefly put, LH helps to promote egg maturation. However, eggs can become *too* mature in a given cycle. Gonal-F might give you slightly less mature eggs, which could be in your favor. Some RE’s use them interchangeably. My RE switched me from Fertinex (similar to Gonal-F) to Pergonal for no real reason, other than I wasn’t getting/staying pg with Fertinex, despite good ovulation and apparently good egg quality. He just figured Pergonal was worth a try (and it just so happened to work, too….clinical pregnancy, carried to term). 2 yrs later, I am presently 14 weeks pg from Gonal-F. In my situation, I don’t think Gonal-F was any better or worse, or more or less effective, than the Pergonal. (my sole cause of infertility is anovulation from PCOS). Other circumstances may vary. Might as well give the Gonal-F a try. Good luck, -Kay
Response:
<<Just to be curious. I understand Pergonal is the same stuff as Menogon (FSH/LH combo). What was the dosage when you started. My RE had me started at one amp per day. It was the same dose as my FSH-only med would have been. I wanted to try a step-down protocol to *minimize* the number of follicles, and it was my idea to start with (I think) 1.5 amps Fertinex (Metrodin HP) then decrease down to 1.0 then 0.5 amps per day. The RE agreed and then in the next breath said, "hey, let’s try Pergonal, instead!". So, we kept the new protocol and switched the med. It did produce the desired results (less quantity, better quality). I didn’t hyperstimulate, I produced only 11 eggs, made 8 embryos, 5 of which went to blastocyst (morula), 1 which became a clinical pregnancy.
Response:
Filed under: PCOS Infertility
Leave a Comment
XHTML: You can use these tags: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>
TrackBack URL | RSS feed for comments on this post.