metformin question

Question:

I have been on gloucophage for awhile, about 7 months now.  What has me puzzled is the reason I am on it.  I was put on it to lower my insulin levels.  What some doctors have told me is that gloucophage lowers the glucose not the insulin.  How is gloucophage working for me if I don’t have high blood sugar. It seems to me this is why the doctors are in conflict about this medication.  Maybe I don’t know enough about how gloucophage works.  Noone explains that gloucophage lowers insulin, as in my case.  Maybe someone should explain that about the drug.  I had an anestiologist tell me he was confused as to why I am on gloucophage if I don’t have blood sugar problems. Donna

Response:

Hi Donna, Glucophage is not labeled as a treatment for PCOS which may be why your anesthesiologist was not familiar with your using it.   The way I understand the process of insulin resistance is, the body has a problem knowing when to produce insulin, and when it does, it overcompensates for being late by sending out too much.  This makes your sugar levels erratic and insulin out of whack. Glucophage helps to control this reaction by lowering the sugar in your bloodstream, before the insulin has a chance to get all crazy in the first place. Jill

Response:

I thought metformin worked by making your cells more sensitive to the insulin.. so your own insulin works better? Jill <jillv…@aol.compost> wrote in message

news:20001112012935.19356.00002193@ng-ch1.aol.com… – Hide quoted text — Show quoted text -> Hi Donna, > Glucophage is not labeled as a treatment for PCOS which may be why your > anesthesiologist was not familiar with your using it. > The way I understand the process of insulin resistance is, the body has a > problem knowing when to produce insulin, and when it does, it overcompensates > for being late by sending out too much.  This makes your sugar levels erratic > and insulin out of whack. > Glucophage helps to control this reaction by lowering the sugar in your > bloodstream, before the insulin has a chance to get all crazy in the first > place. > Jill

Response:

>I thought metformin worked by making your cells more sensitive to the >insulin.. so your own insulin works better?

  Glucophage works within the liver to help the body use the insulin more efficiently. This is unlike the older diabetic drugs of the class of sulfonylureas which stimulate the body to release more insulin–not good for many whose problem was overproduction of insulin in the first place, though a few type 2’s would be simply insulin-deficient and would benefit from this class.  I tend to think of these folks as type 1 and a halfs. :-)  ^—^ Cathy { ‘ . ‘ }       `  Those who play with cats must expect to be scratched. 4Cysters: http://pages.ivillage.com/cystercat Other pages: http://peaceonearth.faithweb.com http://littlec.faithweb.com http://www.i-love-cats.com/meow/cat

Response:

On Sat, 11 Nov 2000 15:56:29 -0500, "Donna" <glen.rem…@rcn.com> wrote: >I have been on gloucophage for awhile, about 7 months now.  What has me >puzzled is the reason I am on it.  I was put on it to lower my insulin >levels.  What some doctors have told me is that gloucophage lowers the >glucose not the insulin.

They’re misinformed.  What kind of docs are you seeing?  General MDs, OB/GYNs, and/or an endocrinologist?   Elise

Response:

Filed under: PCOS Treatment

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