metformin/placebo

Question:

My RE said it takes about a month for the met/gluco to get into your system.  I’ve been on gluco xr for a little over 2 months, 2000 mgs, and have ovulated, lost weight, and it’s curbed my appetite. Just remember everybody’s bodies are different.  What takes one person 2 weeks to work, might take someone else 3 months. Good luck Vick

Response:

<<<<So, lack of side-effects doesn’t necessarily mean you’re in the placebo group.>>>> I agree.  I was on Met up to 1500 mg a day and had NO side effects and no weight loss after two and a half months of being at that level.   Carrie   "People above the line of bare subsistence do not use the surplus which society has given them primarily for useful purposes, <snip>   but to impress other people with the fact that they have a surplus."  ~Stuart

Response:

On 2 Dec 2002 19:32:37 -0800, MFishmanCr…@yahoo.com (Michelle) wrote: – Hide quoted text — Show quoted text ->Hi Jo, >> hi, I’ve just been placed on a UK study into metformin for pcos (apparently its >> not licensed for that over here). I’ve been given two 850 tablets per day which >> could be metformin or could be a placebo. My question is, after 4 days if I’ve >> lost no weight yet and had no significant side effects does that probably mean >> I’m on the placebo? >> Thanks in advance for any opinions/responses. >As far as I’m aware, metformin isn’t licensed for PCOS treatment in >the US, either, but is prescribed because it has helped women with >PCOS, particularly insulin resistance. >I’d say if you haven’t been running to the bathroom lately, chances >are you’re on a placebo.  I did pretty well on 500mgs, no side >effects, on 1000mgs, some side effects, but once it went up to >1500mgs, I had some serious gastro-intestinal problems.  Seeing you’re >on 1700mgs, I would have thought you would’ve noticed some appetite >changes or frequent loo visits.  It might still be early, though. >Give yourself a week–if no side effects, you’re either very fortunate >or you’re part of the placebo group. >Weight loss wouldn’t happen as fast, though, so don’t base your >judgment on that. >Good luck! >Michelle

Which brings to mind.. doesn’t it come in 500mg pills?

Response:

Hi Jo, > hi, I’ve just been placed on a UK study into metformin for pcos (apparently its > not licensed for that over here). I’ve been given two 850 tablets per day which > could be metformin or could be a placebo. My question is, after 4 days if I’ve > lost no weight yet and had no significant side effects does that probably mean > I’m on the placebo? > Thanks in advance for any opinions/responses.

As far as I’m aware, metformin isn’t licensed for PCOS treatment in the US, either, but is prescribed because it has helped women with PCOS, particularly insulin resistance. I’d say if you haven’t been running to the bathroom lately, chances are you’re on a placebo.  I did pretty well on 500mgs, no side effects, on 1000mgs, some side effects, but once it went up to 1500mgs, I had some serious gastro-intestinal problems.  Seeing you’re on 1700mgs, I would have thought you would’ve noticed some appetite changes or frequent loo visits.  It might still be early, though. Give yourself a week–if no side effects, you’re either very fortunate or you’re part of the placebo group. Weight loss wouldn’t happen as fast, though, so don’t base your judgment on that. Good luck! Michelle

Response:

milady wrote: > On 2 Dec 2002 19:32:37 -0800, MFishmanCr…@yahoo.com (Michelle) > wrote: > >I’d say if you haven’t been running to the bathroom lately, chances > >are you’re on a placebo.  I did pretty well on 500mgs, no side > >effects, on 1000mgs, some side effects, but once it went up to > >1500mgs, I had some serious gastro-intestinal problems.  Seeing you’re > >on 1700mgs, I would have thought you would’ve noticed some appetite > >changes or frequent loo visits.  It might still be early, though. > >Give yourself a week–if no side effects, you’re either very fortunate > >or you’re part of the placebo group. > Which brings to mind.. doesn’t it come in 500mg pills?

It comes in either 500 or 850 mg pills. I must be one of the lucky ones, because aside from some very mild nausea I have no GI side effects at all and I’m currently taking 1700 mgs a day and have been for a couple of weeks.  It took four weeks to level up to that dosage, though. So, lack of side-effects doesn’t necessarily mean you’re in the placebo group. -Stephanie, newly diagnosed

Response:

hi, I’ve just been placed on a UK study into metformin for pcos (apparently its not licensed for that over here). I’ve been given two 850 tablets per day which could be metformin or could be a placebo. My question is, after 4 days if I’ve lost no weight yet and had no significant side effects does that probably mean I’m on the placebo? Thanks in advance for any opinions/responses. Jo

Response:

On 01 Dec 2002 16:10:31 GMT, jomc…@aol.com (Jomcmad) wrote: >hi, I’ve just been placed on a UK study into metformin for pcos (apparently its >not licensed for that over here). I’ve been given two 850 tablets per day which >could be metformin or could be a placebo. My question is, after 4 days if I’ve >lost no weight yet and had no significant side effects does that probably mean >I’m on the placebo? >Thanks in advance for any opinions/responses. >Jo

Unfortunately, it doesn’t work that fast for weight loss. If you have frequent visits to the bathroom and some cramping, you are probably taking metformin, although it does affect everyone differently, so it is hard to say for certain. Trina

Response:

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