Polycystic Ovary Syndrome (PCOS) » Polycystic Ovarian

Sunday with Odessa

admin — Mon, 18 Oct 2004 00:00:00 +0000

Question:

Keep those happy purrs coming! I got to hold my Odessa today, but she made me fight for it. She got me going in a game of Chase the Kitty that had me running all over the computer room. She’s very graceful and ran and jumped with a gymnast’s ease of movement. It was a pleasure just to watch her. She ran under the computer I use, not under the big desk where she’s frequently hidden, and after all the running decided to let me pick her up. No hissing or foul language. She let me hold her for several minutes without any struggle, and even started purring after getting her ears and chin scratched. When she did want down, she went to her closet, gave me a short hiss as if to say "That was nice but leave me alone now, I must meditate" and lay down. She let me reach into the closet and give her a quick pet, without any cussing. And when Louie came up to feed her, she didn’t completely run and hide, just ran but peeked out of her closet. I have to say that the other kids have been really nice about having Odessa here. Roxie has taken a guardpost upstairs and has been keeping the Juvies from coming up and trying to butt the door open or generally cause trouble. She seems to know that Odessa will take a little longer to integrate than the outgoing Brandy. Stosh is acting more secure with himself. When we brought in first Roxie, then our fosterling Brian, he was insecure and needed a lot of reassurance. I figured it was related to his background of abuse. When Brandy came, he was nuts to meet her, and they became fast buddies. I have a feeling that Odessa will be more Roxie’s speed; Odessa certainly likes to meditate, I’ve seen that already. And Brandy? She seems completely OK with everything, but she came out of a busy foster home where there was a turnover of animals, and a lot of animals at any given time. She is the only one who doesn’t camp out at the door. She’s too busy playing and wrestling with Stosh, which has become one of my favorite sporting events. Blessed be, Baha

Response:

You’re obviously making progress, Baha; just keep on doing what you’re doing and purrs from us to help you along! Christine (enjoying the stories)

– Hide quoted text — Show quoted text – Keep those happy purrs coming! I got to hold my Odessa today, but she made me fight for it. She got me going in a game of Chase the Kitty that had me running all over the computer room. She’s very graceful and ran and jumped with a gymnast’s ease of movement. It was a pleasure just to watch her. She ran under the computer I use, not under the big desk where she’s frequently hidden, and after all the running decided to let me pick her up. No hissing or foul language. She let me hold her for several minutes without any struggle, and even started purring after getting her ears and chin scratched. When she did want down, she went to her closet, gave me a short hiss as if to say "That was nice but leave me alone now, I must meditate" and lay down. She let me reach into the closet and give her a quick pet, without any cussing. And when Louie came up to feed her, she didn’t completely run and hide, just ran but peeked out of her closet. I have to say that the other kids have been really nice about having Odessa here. Roxie has taken a guardpost upstairs and has been keeping the Juvies from coming up and trying to butt the door open or generally cause trouble. She seems to know that Odessa will take a little longer to integrate than the outgoing Brandy. Stosh is acting more secure with himself. When we brought in first Roxie, then our fosterling Brian, he was insecure and needed a lot of reassurance. I figured it was related to his background of abuse. When Brandy came, he was nuts to meet her, and they became fast buddies. I have a feeling that Odessa will be more Roxie’s speed; Odessa certainly likes to meditate, I’ve seen that already. And Brandy? She seems completely OK with everything, but she came out of a busy foster home where there was a turnover of animals, and a lot of animals at any given time. She is the only one who doesn’t camp out at the door. She’s too busy playing and wrestling with Stosh, which has become one of my favorite sporting events. Blessed be, Baha

Response:

Odessa certainly likes to meditate, I’ve seen that already. And Brandy? She seems completely OK with everything, but she came out of a busy foster home where there was a turnover of animals, and a lot of animals at any given time. She is the only one who doesn’t camp out at the door. She’s too busy playing and wrestling with Stosh, which has become one of my favorite sporting events. Blessed be, Baha

Sounds like things are going great. I’m glad Roxy is helping out. Suz Macmoosette Thank Heavens There’s Only One =^..^= =^..^= =^..^= =^..^= =^..^= =^..^= Waiting for inspiration. Please hold while I contemplate my navel. |__/| (=’:'=) (")_(")

Response:

So glad she seems to be settling in a bit. You know what you’re doing, don’t you, Baha, you are *spoiling yourself* with cats! Odessa sounds like she’ll be a gentle and thoughtful cat, like my Boyfriend. I’m sure she’ll fit in just fine very soon. It must be scary when they go to a different place that they don’t know and are not sure what dangers they face there, and what might happen. Scritches to Odessa. The lucky girl. Tweed

Response:

I’m hoping that she is learning that she is safe with you and with Louie. It must be so terrible hard to her. Different sounds and smells and furniture. She is probably imagining that the other cats are monsters who want to gobble her up. Can’t blame a girl for being cautious. She really has no experience to expect what a nice home she has landed in. Jo

Response:

So glad she seems to be settling in a bit. You know what you’re doing, don’t you, Baha, you are *spoiling yourself* with cats!

Is that possible? Maybe it’s the Mama in me. I have polycystic ovarian disorder, which at my age makes me nearly infertile, and the only treatment makes damn sure that I am infertile. It’s not fatal, only makes my uterus useful for PMS. The cats are my babies. I adored my Fritzie when he was with us, but he was destined to be an only child; his health was so delicate we didn’t want to screw up his diabetes with the stress of another cat. Now the Mama in me wants her babies. The life and activity in this house with multiple cats is simply a delight. Even my Louie feels like the King of the pride when he’s slopping around watching The Big Game, and all the cats are curled around him. Odessa sounds like she’ll be a gentle and thoughtful cat, like my Boyfriend.

What a delightful name for a cat! I love it. And you know what, sometimes a cat is a heluva lot more reliable and thoughtful than a man. Or ladies, for you guys who’ve been burned. (No offense to you good fellows here, but every girl on this board has known at least one commitment-phobe or serial dater in her lifetime!) Odessa is coming more out of her shell, and I do see that she is very gentle and that she has a lot of affection deep in her little heart. She just has a lot of adjusting to do yet, the poor baby; she’s been through a lot and has had a lot of rejection. I’m sure she’ll fit in just fine very soon. It must be scary when they go to a different place that they don’t know and are not sure what dangers they face there, and what might happen. Scritches to Odessa. The lucky girl.

The lucky Mama will pass on the scritches. Many thanks! Blessed be, Baha

Response:

So glad she seems to be settling in a bit. You know what you’re doing, don’t you, Baha, you are *spoiling yourself* with cats! Is that possible?

No, I was just teasing you, Mrs Kaur. Tweed

Response:

You sound like you are going to have a balanced pet brigade. Cheers for you and Odessa in the bonding game. — CATherine

Response:

Dumb Questions About Glucophage (pg, m/c ment)

admin — Sun, 18 Mar 2001 00:00:00 +0000

Question:

I just found this newsgroup and I was just checking it out when I saw your post. I was diagnosed with PCOS about 7 months ago. I started Glucophage right away but unfortunatly this medicine alone would not bring on AF. I have to take Prometrium starting day 35 of my cycle(every month). As far as the weight loss, I have lost 35lbs so far since stating meds, and I have not changed my eating habits(and, unfortunatly, they aren’t very good!!) Good Luck, Michelle

Response:

Hey Ladies, Allow me to give you some background first: I DO NOT have high blood sugar. My glucose and insulin are both normal. In fact all of the other protocol testing for the syndrome itself are normal, not even borderline, just right down the middle, normal. I DO have polycystic ovaries. I DO NOT ovulate on my own and therefore would get a period only God knows when. I DO have facial hair. It’s light, not dark or coarse. My upper lip is the most annoying. I WAS pg. last October after Gonal-F and IUI and m/c twins in December 2000. My doctor DID prescribe Glucophage for me. 500 mg once a day for 7 days, then twice a day for 7 days then three times a day from then on. I DO eat very well. Lots of good food. No red meat, no dairy, no white breads, no refined sugar and no sweets. Only carbos I eat are some form of pasta once a week. Here are my questions: 1. When can I perhaps expect my first period to come if the Glucophage works for me? This is the end of week two(1000 mg) and tomorrow I begin 1500. 2. How much weight can I lose on this stuff and when in the world can I expect to see it happen? Do I need to be on the whole 1500 mg/day to see the effects? I work out every other day at least in addition. I gained 40 pounds on all of the fertility drugs and of course from the 13 weeks of pg. 3. Since the doctor found some fluid in the endometrium, presumably a small clotting of blood, left over from the m/c, how will I know I am actually having a period? 4. On average, when AF returns, what kins of recurring cycle time frames are you all getting? 5. I never had acne as a teenager but have developed some mild adult acne and use Clearasil. It seems to have cleared a little since starting the Glucophage. Did anyone else experience this? Thanks in advance for any help. Theresa

Response:

Everyone reacts differently. I’ve been on 1500mg since last may and my cycles are still not regular. In october I had ovarian drilling and since then I have non-drug induced periods every couple of months. I’ve just recently had my dosage increased to 1700mg a day, so we shall see what happens. Since starting I don’t have to shave more than once a day and if I want I can actually skip a day of shaving. My facial hair growth has greatly decreased. I have lost 10lbs and been able to keep it off. You just need to keep in mind that everyone reacts differently. Mandy Martensen – Hide quoted text — Show quoted text -Theresa Nelson wrote: > Hey Ladies, > Allow me to give you some background first: > I DO NOT have high blood sugar. My glucose and insulin are both > normal. In fact all of the other protocol testing for the syndrome > itself are normal, not even borderline, just right down the middle, > normal. > I DO have polycystic ovaries. > I DO NOT ovulate on my own and therefore would get a period only God > knows when. > I DO have facial hair. It’s light, not dark or coarse. My upper lip is > the most annoying. > I WAS pg. last October after Gonal-F and IUI and m/c twins in December > 2000. > My doctor DID prescribe Glucophage for me. 500 mg once a day for 7 > days, then twice a day for 7 days then three times a day from then on. > I DO eat very well. Lots of good food. No red meat, no dairy, no white > breads, no refined sugar and no sweets. Only carbos I eat are some form > of pasta once a week. > Here are my questions: > 1. When can I perhaps expect my first period to come if the Glucophage > works for me? This is the end of week two(1000 mg) and tomorrow I begin > 1500. > 2. How much weight can I lose on this stuff and when in the world can I > expect to see it happen? Do I need to be on the whole 1500 mg/day to > see the effects? I work out every other day at least in addition. I > gained 40 pounds on all of the fertility drugs and of course from the 13 > weeks of pg. > 3. Since the doctor found some fluid in the endometrium, presumably a > small clotting of blood, left over from the m/c, how will I know I am > actually having a period? > 4. On average, when AF returns, what kins of recurring cycle time > frames are you all getting? > 5. I never had acne as a teenager but have developed some mild adult > acne and use Clearasil. It seems to have cleared a little since > starting the Glucophage. Did anyone else experience this? > Thanks in advance for any help. > Theresa

Response:

I started on Glucophage last November. I had a period 2 weeks after my first dose. Since then, my cycles have been 28-34 days long. Before starting Glucophage, I would have a period every 3 months or so, so it is working. I didn’t have a problem with acne, so I can’t help you there. Biss "Theresa Nelson" wrote in message

news:3AB52847.8BA10DFD@home.com… – Hide quoted text — Show quoted text -> Hey Ladies, > Allow me to give you some background first: > I DO NOT have high blood sugar. My glucose and insulin are both > normal. In fact all of the other protocol testing for the syndrome > itself are normal, not even borderline, just right down the middle, > normal. > I DO have polycystic ovaries. > I DO NOT ovulate on my own and therefore would get a period only God > knows when. > I DO have facial hair. It’s light, not dark or coarse. My upper lip is > the most annoying. > I WAS pg. last October after Gonal-F and IUI and m/c twins in December > 2000. > My doctor DID prescribe Glucophage for me. 500 mg once a day for 7 > days, then twice a day for 7 days then three times a day from then on. > I DO eat very well. Lots of good food. No red meat, no dairy, no white > breads, no refined sugar and no sweets. Only carbos I eat are some form > of pasta once a week. > Here are my questions: > 1. When can I perhaps expect my first period to come if the Glucophage > works for me? This is the end of week two(1000 mg) and tomorrow I begin > 1500. > 2. How much weight can I lose on this stuff and when in the world can I > expect to see it happen? Do I need to be on the whole 1500 mg/day to > see the effects? I work out every other day at least in addition. I > gained 40 pounds on all of the fertility drugs and of course from the 13 > weeks of pg. > 3. Since the doctor found some fluid in the endometrium, presumably a > small clotting of blood, left over from the m/c, how will I know I am > actually having a period? > 4. On average, when AF returns, what kins of recurring cycle time > frames are you all getting? > 5. I never had acne as a teenager but have developed some mild adult > acne and use Clearasil. It seems to have cleared a little since > starting the Glucophage. Did anyone else experience this? > Thanks in advance for any help. > Theresa

Response:

Falling hair

admin — Sun, 26 Nov 2000 00:00:00 +0000

Question:

Dear Jodi, Hadn’t thought of that but I bet your right. Rusty

Response:

Jodi, Yeah, I’ve been trying to increase my fat intake and make sure that I am getting enough of that. I don’t really think it’s a sugar thing, but maybe. I’ll talk to my therapist some about it tomorrow. Hugs, Kerri "The real gold has always been the individual spirit…" – Tori Amos "this I swear you’re the fiercest calm I’ve been in" T. Amos

Response:

Excerpts from netnews.alt.support.eating-disord: 28-Nov-100 Re: Falling Eat more protien my dear and lay off the sugar.

not neccassarily… not on both counts, at least. my own experience with hair has been, the amount of protein you eat doesn’t matter a bit. it is VERY VERY hard to not get enough protein. the need for protein is highly overestimated in most cases. what i have found to matter is fat. yes, FAT. eat some. i swear, in my experience, i could eat all the egg beaters and fat free cheese in the world and my hair still fell out and looked like shit. i thought it was a protein thing, too. but i think it’s a fat thing. honest. try eating more fat. try eating ENOUGH fat. with that said, try a multi vitamin perhaps? and with THAT said, have your homrone levels checked. i have recently been diagnosed with polycystic ovarian syndome. i think that this might be the underlying cause of my ED. it stems from a problem with insulin production… a sort of reverse diabetes if you will. excess insulin results in sky high andorgens which in turn result in missed periods, excess body hair, inability to lose weight, and baldness. yes it’s ironic that the same thing that makes you grow excess body hair can also make you lose the hair on your head. so if nutrition is really under wraps – and i mean you are honest to god eating healthy and not just eating "anorexic healthy" – and you are still losing your hair i’d highly suggest looking for a hormonal problem if you are losing that much hair. i mean, it is possible that it’s the stress of returning to nutrition, etc that is causing this… but if it’s getting worse, or doesn’t go away, it’s something to look into. it means, in a way, cutting down on sugar could help. but eating more protein probably won’t change a thing. – jodi <*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<* it was only fantasy – the wall was too high, as you can see no matter how he tried, he could not break free and the worms ate into his brain… – pink floyd <*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*=<*

Response:

Eat more protien my dear and lay off the sugar. Rusty "

Response:

Hi Kerri! I’m sorry you’re having this problem. I really feel for you, as I know personally what it’s like. I know you said you don’t see your nutritionist until mid December. But I am wondering if you could call & talk to her about this, since it is worrying you? Ears There can be no transforming of darkness into light and of apathy into movement without emotion. – Carl Jung The voyage of discovery lies not in finding new landscapes but in having new eyes. – Marcel Proust

Response:

Hey Kerri I have found that my hair loss is worse when I am eating properly, for about 6 months and the slows down. My friends have found that to – it’s worse when nourished than when starving, so take it as a good sign. Kind of like your body getting rid of the unhealthy hair to make room for new healthy hair to grow. love, aria You are led through your lifetime by the inner learning creature, the playful being that is your real self. Don’t turn away from any possible futures before your’re certain you don’t have anything to lern from them. You are always free to change your mind and choose a different future, or a different past. Illusions

Response:

Lucy, Thanks for the input. Actually, you didn’t scare me I’ve been through the hair loss before only last time it tapered off fairly quickly. I’m hoping that what happened to you doesn’t happen to me!!!! No offense, it took me so long to grow my hair out and I’m not willing to lose it all! I’ll do whatever it takes for me to stop this….well except eating meat….but perhaps I should definately up my proteing for a while I believe. I’m eating plenty of protein but I but I should up it even further. Kerri "The real gold has always been the individual spirit…" – Tori Amos "this I swear you’re the fiercest calm I’ve been in" T. Amos

Response:

Dear Kerri, I’m wondering if anyone knows how long it takes for one’s hair to stop falling out after stopping ed behaviours and returning to a "normal" diet.

I don’t mean to scare you, but I lost most ALL of my hair AFTER I had begun recovery, had regained a lot of weight, and was eating healthily. That is just my experience though. I borrowed quite a few baseball caps during that period! Hang in there, the best thing you can do now is to keep nourishing your body to prevent further damage. Good luck, Lucy

Response:

OK, you just scared me a lot… how far into people’s EDs did they come upon this problem?? Lori

Response:

Thanks for the reply Jc! I was attracted to your post because your subject header "falling hair" sounded so poetic.

perhaps I should write a recovery poem about it then? Actually, I am a poet. I’m majoring in English with a concentration on Creative writing and am currently studying with the Poet Laureate for the state of Ga (can you tell that I LOVE that class?) and he is an amazing professor and I’m learning lots. Hugs, Kerri "The real gold has always been the individual spirit…" – Tori Amos "this I swear you’re the fiercest calm I’ve been in" T. Amos

Response:

Dear Kerri, I was attracted to your post because your subject header "falling hair" sounded so poetic. I know that is not what your post is about, but it is a really nice combination of words. Even though what they signify for you is not so fun. My own hair tends not to fall out too much, but it did once. Here is what I have heard from others. I have one friend whose hair falls out only after she begins to recover her weight. The same thing happened with a young woman in my ED group. She ended up dying her hair blond so it wouldn’t be so obvious. Once when I was getting bald spots I just cut my hair. My hair is curly, so it curled around the bald spots and made them less obvious. I am not sure how long the hair falling out lasts. It could be a while. If you are self-conscious about it, have you thought about a bandana — they are in style now and it would help keep you warm in the winter weather. I also used a hair band to gather my hair together and away from my face to mask its falling out. I know what a horrible feeling it is–clump after clump. It will stop–on it’s own time. There are some herbs and vitamens, I believe that help people — I don’t know what they are. I had a roommate that took them to keep her hair from falling out more due to a thyroid medicine. hang in there, jc

Response:

Hi guys, Okay, so I’m wondering if anyone knows how long it takes for one’s hair to stop falling out after stopping ed behaviours and returning to a "normal" diet. My hair is STILL falling out in clumps and it’s been about 2 months or so (yes I know that’s a short time but it seems like it would have slowed down) and I think it may be worse now than it was before. I’ll ask my nutritionist about it next time I see her, but I don’t see her again until mid December. Anyway, just wondering if anyone knows how much longer I can expect my hair to fall out….I swear I’m starting to see bald spots and that’s a major deal for someone with waist length hair (or near there anyway…it’s about 2 inches above). Hugs, Kerri "The real gold has always been the individual spirit…" – Tori Amos "this I swear you’re the fiercest calm I’ve been in" T. Amos

Response:

clomiphine, igf-1 and pcos

admin — Sat, 04 Nov 2000 00:00:00 +0000

Question:

My son, now 6 months old, was concieved on 150 mg of clomiphene. In addition, my first pregnancy, which miscarried early on, was achieved on 100 mg of clomiphene. This put me up to a grand total of 10 months total of clomophene, but I had no reactions. So I know that it does work for some women, but have heard that not all PCOS women can get pregnant on Clomid (the brand name). Carrie — Cleverly Disguised As A Responsible Adult rie…@miribiledictu.net http://www.miribiledictu.net Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

>i was on clomiphene for 6 months, way past the 3 month recommendation.

I was on Clomid for 3 years with no adverse reactions. I went off when finally getting pregnant with my now 10 year old daughter.

Response:

i was on clomiphene for 6 months, way past the 3 month recommendation. i did finally ovulate one night. i got terrible middlescmertz (ovulatory pain)one night when i was out to dinner.the only time ever in my life that i felt it. i had a baby nine months later. the second round 2 years later i started breaking out in welts head to toe. i tried everything to make it work, my re put me on a steroid even to keep the allergic reaction down. but each dose the reaction got worse and i had to go to injectables instead. kooky. barb In article <8u13nm$ag…@nnrp1.deja.com>, wuzzy wrote: – Hide quoted text — Show quoted text -> Clomiphine is apparently the most commonly prescribed drug for > inducing ovulation in PCOS… > anyway, new studies seem to suggest that it does this despite no > alterations in insulin resistance… the suggested mechanism is that it > reduces IGF-1 (a GH-related hormone that increases androgens) > anyway, thats from this month’s human reproduction: > has anyone tried clomiphine with success? I’m curious as to whether it > affects androgen levels even though it doesn’t affect Insulin > resistance.. > 1: Hum Reprod 2000 Nov;15(11):2302-2305 > Related > Articles, Books, LinkOut > Clomiphene citrate increases insulin-like growth > factor binding > protein-1 and reduces insulin-like growth > factor-I without > correcting insulin resistance associated with > polycystic ovarian > syndrome. > De Leo V, la Marca A, Morgante G, Ciotta L, > Mencaglia L, Cianci A, Petraglia > F > Department Obstetrics and Gynecology, University > of Study of Siena, > Department Obstetrics and Gynecology, University > of Study of Catania and > Centro Florence, Firenze, Italy. > [Record supplied by publisher] > The induction of ovulation by clomiphene could be > the result of interaction of > the drug at various levels: hypothalamus, > pituitary and ovary. It was > demonstrated that administration of clomiphene to > women with polycystic > ovarian syndrome (PCOS) is accompanied by a > reduction in plasma > concentrations of insulin-like growth factor-I > (IGF-I). IGF-I seems to have an > overall negative effect on normal > folliculogenesis and ovulation. The aim of the > present study was to evaluate the effect of > clomiphene on plasma > concentrations of IGF-I and IGF binding protein > (IGFBP)-1 and on insulin > resistance associated with PCOS. Fifteen patients > diagnosed with PCOS were > recruited. Clinical diagnosis was based on > chronic oligomenorrhoea or > amenorrhoea and hyperandrogenaemia. Clomiphene > citrate was administered at > a dose of 100mg/day to all women from day 5 to > day 9 of the spontaneous or > medroxyprogesterone acetate (MAP)-induced > menstrual cycle. Blood sampling > and a 2 h oral glucose loading test (75 g) were > performed the day before and > after the course of clomiphene. Ovulation was > confirmed in 13/15 PCOS > patients. Plasma concentrations of IGF-I > decreased by 31.5% (434 +/- 84 versus > 297 +/- 71 ng/ml; P: < 0.05) after 5 days of > clomiphene therapy, whereas plasma > concentrations of IGFBP-1 increased by > approximately 28.1% (26.3 +/- 4 versus > 36.6 +/- 7 ng/ml; P: < 0.05). This gave a 56.5% > reduction in the IGF-I:IGFBP-1 > ratio (21.9 versus 9.53). No significant changes > in basal plasma concentrations > of fasting insulin or area under the insulin > curve were observed in response to > oral loading. The present results show that > clomiphene does not cause changes > in insulin resistance associated with PCOS but > reduces plasma concentrations > of IGF-I and increases those of IGFBP-1, with a > consequent marked reduction in > the IGF-I:IGFBP-1 ratio. > Sent via Deja.com http://www.deja.com/ > Before you buy.

Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

My dh and I were successful on one round of Clomiphene, or Clomid as it is commonly know. We now are proud parents of son, Evan Matthew, born 07/27/00. However, alot of women with PCOS do not respond to clomid. Shannon In article <8u13nm$ag…@nnrp1.deja.com>, wuzzy wrote: – Hide quoted text — Show quoted text -> Clomiphine is apparently the most commonly prescribed drug for > inducing ovulation in PCOS… > anyway, new studies seem to suggest that it does this despite no > alterations in insulin resistance… the suggested mechanism is that it > reduces IGF-1 (a GH-related hormone that increases androgens) > anyway, thats from this month’s human reproduction: > has anyone tried clomiphine with success? I’m curious as to whether it > affects androgen levels even though it doesn’t affect Insulin > resistance.. > 1: Hum Reprod 2000 Nov;15(11):2302-2305 > Related > Articles, Books, LinkOut > Clomiphene citrate increases insulin-like growth > factor binding > protein-1 and reduces insulin-like growth > factor-I without > correcting insulin resistance associated with > polycystic ovarian > syndrome. > De Leo V, la Marca A, Morgante G, Ciotta L, > Mencaglia L, Cianci A, Petraglia > F > Department Obstetrics and Gynecology, University > of Study of Siena, > Department Obstetrics and Gynecology, University > of Study of Catania and > Centro Florence, Firenze, Italy. > [Record supplied by publisher] > The induction of ovulation by clomiphene could be > the result of interaction of > the drug at various levels: hypothalamus, > pituitary and ovary. It was > demonstrated that administration of clomiphene to > women with polycystic > ovarian syndrome (PCOS) is accompanied by a > reduction in plasma > concentrations of insulin-like growth factor-I > (IGF-I). IGF-I seems to have an > overall negative effect on normal > folliculogenesis and ovulation. The aim of the > present study was to evaluate the effect of > clomiphene on plasma > concentrations of IGF-I and IGF binding protein > (IGFBP)-1 and on insulin > resistance associated with PCOS. Fifteen patients > diagnosed with PCOS were > recruited. Clinical diagnosis was based on > chronic oligomenorrhoea or > amenorrhoea and hyperandrogenaemia. Clomiphene > citrate was administered at > a dose of 100mg/day to all women from day 5 to > day 9 of the spontaneous or > medroxyprogesterone acetate (MAP)-induced > menstrual cycle. Blood sampling > and a 2 h oral glucose loading test (75 g) were > performed the day before and > after the course of clomiphene. Ovulation was > confirmed in 13/15 PCOS > patients. Plasma concentrations of IGF-I > decreased by 31.5% (434 +/- 84 versus > 297 +/- 71 ng/ml; P: < 0.05) after 5 days of > clomiphene therapy, whereas plasma > concentrations of IGFBP-1 increased by > approximately 28.1% (26.3 +/- 4 versus > 36.6 +/- 7 ng/ml; P: < 0.05). This gave a 56.5% > reduction in the IGF-I:IGFBP-1 > ratio (21.9 versus 9.53). No significant changes > in basal plasma concentrations > of fasting insulin or area under the insulin > curve were observed in response to > oral loading. The present results show that > clomiphene does not cause changes > in insulin resistance associated with PCOS but > reduces plasma concentrations > of IGF-I and increases those of IGFBP-1, with a > consequent marked reduction in > the IGF-I:IGFBP-1 ratio. > Sent via Deja.com http://www.deja.com/ > Before you buy.

– Shannon First-time Mommy to Evan 07/27/00 PCOS diagnosed 1989 Rezulin / Clomid Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

Clomiphine is apparently the most commonly prescribed drug for inducing ovulation in PCOS… anyway, new studies seem to suggest that it does this despite no alterations in insulin resistance… the suggested mechanism is that it reduces IGF-1 (a GH-related hormone that increases androgens) anyway, thats from this month’s human reproduction: has anyone tried clomiphine with success? I’m curious as to whether it affects androgen levels even though it doesn’t affect Insulin resistance.. 1: Hum Reprod 2000 Nov;15(11):2302-2305 Related Articles, Books, LinkOut Clomiphene citrate increases insulin-like growth factor binding protein-1 and reduces insulin-like growth factor-I without correcting insulin resistance associated with polycystic ovarian syndrome. De Leo V, la Marca A, Morgante G, Ciotta L, Mencaglia L, Cianci A, Petraglia F Department Obstetrics and Gynecology, University of Study of Siena, Department Obstetrics and Gynecology, University of Study of Catania and Centro Florence, Firenze, Italy. [Record supplied by publisher] The induction of ovulation by clomiphene could be the result of interaction of the drug at various levels: hypothalamus, pituitary and ovary. It was demonstrated that administration of clomiphene to women with polycystic ovarian syndrome (PCOS) is accompanied by a reduction in plasma concentrations of insulin-like growth factor-I (IGF-I). IGF-I seems to have an overall negative effect on normal folliculogenesis and ovulation. The aim of the present study was to evaluate the effect of clomiphene on plasma concentrations of IGF-I and IGF binding protein (IGFBP)-1 and on insulin resistance associated with PCOS. Fifteen patients diagnosed with PCOS were recruited. Clinical diagnosis was based on chronic oligomenorrhoea or amenorrhoea and hyperandrogenaemia. Clomiphene citrate was administered at a dose of 100mg/day to all women from day 5 to day 9 of the spontaneous or medroxyprogesterone acetate (MAP)-induced menstrual cycle. Blood sampling and a 2 h oral glucose loading test (75 g) were performed the day before and after the course of clomiphene. Ovulation was confirmed in 13/15 PCOS patients. Plasma concentrations of IGF-I decreased by 31.5% (434 +/- 84 versus 297 +/- 71 ng/ml; P: < 0.05) after 5 days of clomiphene therapy, whereas plasma concentrations of IGFBP-1 increased by approximately 28.1% (26.3 +/- 4 versus 36.6 +/- 7 ng/ml; P: < 0.05). This gave a 56.5% reduction in the IGF-I:IGFBP-1 ratio (21.9 versus 9.53). No significant changes in basal plasma concentrations of fasting insulin or area under the insulin curve were observed in response to oral loading. The present results show that clomiphene does not cause changes in insulin resistance associated with PCOS but reduces plasma concentrations of IGF-I and increases those of IGFBP-1, with a consequent marked reduction in the IGF-I:IGFBP-1 ratio. Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

anyone have Polycystic Ovarian Diasese…..HELP ME PLEASE!!!!!

admin — Tue, 16 Mar 1999 00:00:00 +0000

Question:

I am a 20/f in Ohio…i have been diagnosed with this about 2 1/2 years ago….i am unable to become pregnant so they day…i would like to talk to

Response:

Try this site http://www.netcolony.com/members/pcolc/pcolc.html Research! Research! Research! You will find so many answers to your questions! Goodluck to you! Chris Wife to Gregg Mommy to Maddy (7), Diagnosed with PCOS in Aug 98 TTC #2

Response:

The whole name is alt.support.pco Good luck, it’s not as bad at is seems. – Hide quoted text — Show quoted text – I am a 20/f in Ohio…i have been diagnosed with this about 2 1/2 years ago….i am unable to become pregnant so they day…i would like to talk to

Response:

There is a great newsgroup about Polycystic Ovarian Diasese support.pco – Hide quoted text — Show quoted text – I am a 20/f in Ohio…i have been diagnosed with this about 2 1/2 years ago….i am unable to become pregnant so they day…i would like to talk to

Response:

Hi! I am 22 and I was diagonised with PCO in August of 98′. We are still trying. If you want to talk, please feel free to e-mail me. Tammy

Response:

Hi there!

I’m 31 and diagnosed with mild polycystic ovaries last Monday. It took a while to have it diagnosed, but at least now I know . It doesn’t make pregnancy easy, but there’s treatments for it. I’ll go on clomid in two weeks and keep my hopes high! .there’s a lot of help out there. I am quite new here, but if there’s anything I can help you with, please write to me… Good luck Roser

Response:

Metformin and meals.

admin — Wed, 27 Jan 1999 00:00:00 +0000

Question:

<< I got it at GNC, and the flavor is a delicate chocolate. >> I’ve recently discovered, thanks to the low carb newsgroup, that you can also buy it online at a substantial discount. DSN – Discount Sport Nutrition The site is slow and a little cumbersome (you have to hunt around for the Optimum Nutrition protein powder), but for the 1 lb. container, it’s just $12.95 compared to $19.99 at GNC. The 2 lb. container is just $22.95 compared to $35.99 at GNC. Plus, they have more flavors, though I’m hooked on the chocolate. Take care… Kathleen

Response:

In article <19990203194828.21962.00000…@ng96.aol.com>, katcr…@aol.com – Hide quoted text — Show quoted text -(Katcrash) wrote: > << I got it at GNC, and the flavor is a delicate chocolate. >> > I’ve recently discovered, thanks to the low carb newsgroup, that you can also > buy it online at a substantial discount. > DSN – Discount Sport Nutrition > The site is slow and a little cumbersome (you have to hunt around for the > Optimum Nutrition protein powder), but for the 1 lb. container, it’s just > $12.95 compared to $19.99 at GNC. The 2 lb. container is just $22.95 compared > to $35.99 at GNC. > Plus, they have more flavors, though I’m hooked on the chocolate. > Take care… Kathleen

Kathleen.. With the shipping charges, it is still lower? I would love to buy it online if it’s even just a little cheaper Thanks!!!! Karen p.s. you got me hooked on these shakes, lady!!

Response:

Dear, Dear Louise!!! I just tried your recipe for the low carb shake, and let me tell you, I could be in love!! The only thing I added was 1 teaspoon of dry sugar-free jello (orange flavor) and it tasted exactly like that decadent thing that McDonalds sells in the summer. I am a thoroughly happy camper now! YUMMMMM! Oh- I didn’t have heavy cream, so I used 1/2 cup half and half. Also, because I added the jello (thanks to Barb. Agnew) I reduced the equals to 3 packets, and it was plenty sweet enough. For everyone else, I used the GNC protein powder (0 carbs) unsweetened. LIFE IS GOOD! Thanks a million, Louise! Sincerely- Barbara – Hide quoted text — Show quoted text -Louise Taylor wrote: > Leveritt Family wrote: > > Hi Wende! > > I got it at GNC, and the flavor is a delicate chocolate. I just had > > some for breakfast, and I’m happy to report that it fills you up and > > lasts me well past lunch time. It tastes good (I mix mine with half and > > half and ice cubes, so it becomes a slurpy)!! > I found a recipe on a website for this low-carb shake. Ohmigod, it’s to > die for. > 1/4 cup cottage cheese > 1/4 cup cream > 1/4 cup water (I usually add more cause it doesn’t pour well otherwise) > 1/4 cup egg beaters > 1 Tablespoon Protein Powder > 1/4 teaspoon sugar free vanilla (I use Spice Islands pure vanilla) > 6 artificial sweetner tablets or 3 sweetner packets but the packets have > more carbs > 1 cup crushed ice or 7 ice cubes > You can add one tablespoon unsweetened cocoa but that adds carbs. You > could also add strawberries. > Anyway, give it a try. You will be hooked for life. I look forward to my > shake at lunch now. :-) > Louise

Response:

Louise, I would like to put this recipe on a website that I am working on, for Polycystic Ovarian Women Who Are Low-Carbing (PCOLC) Would you mind giving me the site where you found this delicious recipe, so that I will give proper credit/get approval?? Thanks so much!! Karen p.s. the site is http://www.netcolony.com/members/pcolc/pcolc.html – Hide quoted text — Show quoted text -> I found a recipe on a website for this low-carb shake. Ohmigod, it’s to > die for. > 1/4 cup cottage cheese > 1/4 cup cream > 1/4 cup water (I usually add more cause it doesn’t pour well otherwise) > 1/4 cup egg beaters > 1 Tablespoon Protein Powder > 1/4 teaspoon sugar free vanilla (I use Spice Islands pure vanilla) > 6 artificial sweetner tablets or 3 sweetner packets but the packets have > more carbs > 1 cup crushed ice or 7 ice cubes > You can add one tablespoon unsweetened cocoa but that adds carbs. You > could also add strawberries. > Anyway, give it a try. You will be hooked for life. I look forward to my > shake at lunch now. :-) > Louise

Response:

Flax oil is kind of like olive oil, in that it’s one of the "good" fats. If I remember correctly, it’s rich in Omega 3-6-9. I blend up a tablespoon in every shake because I have a hard time keeping my calories up, especially my fat calories. That’s pretty important in low carbing, but I just don’t like my food drowned in mayo or butter. The flax oil lets me up my fat ratio without even knowing it, and in a good, healthy way. I bought a little bottle for $10 at GNC (I think it’s the GNC brand), and that should last a long time. I’m so glad you liked the shake, Barbara. I talk about that brand so much on this board, I’m bordering on obnoxious. But it’s truly made low carbing possible for me. Sometimes, I just get too busy to spend tons of time in the kitchen. Til now, every soy/milk/whey protein shake I’ve tried has tasted like watered down soil. And not eating just isn’t the way to go on this WOE. Take care… Kathleen <>

Response:

Katcrash wrote: >I don’t know, I’m real particular about my chocolate milk, and to me, the >Optimum Nutrition 100% Egg Protein really is excellent when you make it with >two parts cold water and one part heavy cream.

Hmmmmm…. wonder if it’s available in Australia…

Response:

<< Hmmmmm…. wonder if it’s available in Australia… >> I just found out about this website yesterday… you might want to try it: Nutrition Discounters, Inc. Sports Nutrition-Po

Natural remedy on Polycystic Ovarian Symptom

admin — Sun, 24 Jan 1999 00:00:00 +0000

Question:

Hi, Any natural remedy or suggestion on curing the Polycystic Ovarian Symptom before trying to get pregnant? Thanks.

Response:

If it’s secondary to hyperinsulinemia, you’ll start low carb eating, and probably get treated with metformin. But your first stop? try the newsgroup alt.support.pco And you might browse http://centerforpcos.bsd.uchicago.edu/ Good luck! — Karan Davis Harp http://members.tripod.com/~laughlines/index.html

Response:

I'm pretty sure i have PCOS

admin — Sat, 16 Jan 1999 00:00:00 +0000

Question:

I’m pretty sure I have PCOS…I have the sudden hair, real faint on upper lip and really really faint on cheeks but was never there before…I also have the break out on chin mostly but all along the jaw line too. I went to the dermatologist and he prescribed some stuff, seemed to be working but today about 10 more popped out! =( The only thing I DON’T have is the lack of a menstrual cycle or a weird or varying cycle time. My question is, do I go to my ob/gyn or my family doctor? And when I do what do I ask for? I want to get tested and I need to know that my doctor knows what PCO is! Thanks for the help to all of you. Kym

Response:

You need to talk to your doctor because there is a chance it could be something else. Polycystic ovarian syndrom has a LOT to do with the lack of period and if you are not having a problem there, the chances of it being PCOS is hard to believe.

Response:

I have very similar symptoms as yours and suspect pcos. I’ve been told that you can still have period and still have pcos.

Response:

>I’m pretty sure I have PCOS…I have the sudden hair, real faint on upper >lip and really really faint on cheeks but was never there before…I also >have the break out on chin mostly but all along the jaw line too. I went to >the dermatologist and he prescribed some stuff, seemed to be working but >today about 10 more popped out! =( The only thing I DON’T have is the lack >of a menstrual cycle or a weird or varying cycle time.

I’ve had PCOS symptoms since puberty, but my periods did not become irregular until I was about 22 (I’m now almost 25). I also never had any cysts detected. So, I wonder if I continued to get my periods but not ovulate (or not ovulate all the time) simply because I don’t form cysts. My doctor diagnosed me with PCOS due to my low estrogen and progesterone and high insulin. In my opinion, it doesn’t matter which kind of doctor you see. I had no luck with 1 reproductive endocrinologist, 2 endocrinologists, and an ObGyn. Perhaps you should call around and ask how familiar the doctors are with PCOS and if they know of the most recent treatment options available (metformin and rezulin).

Response:

Ovarian drilling… what is it?

admin — Wed, 15 Jul 1998 00:00:00 +0000

Question:

Ovarian drilling takes the place of the "old" method of ovarian wedge resection to treat Polycystic Ovaries. It is intended to "take away" some of the cysts that are putting out too much estrogen(?), thus getting your hormones back in order. There are risks: possible adhesions(scar tissue) which happened to me, from a resection, and now our only hope for a bio-baby is IVF due to severe recurring adhesions that have pinched my tubes closed. hope this has helped you. prayers to ya’ll! Jim & Tam in Houston, Tx. trying for 10 yrs.

Response:

I spoke to my RE today after receiving my monthly pest yesterday. I have been trying almost 2 years. Gone thru 7 months of 150 mg clomid, 5 IUIs w/HCG shots and last month premarin. I produce usually 2 great size follicles. Last month there were 3. But nothing has happened and DH has enough sperm to populate the world a million times over!! Last month he said to think about injectables but my husband works for Bell and they maybe striking in August so I decided to hold off on ALL treatments a few months. Plus I need the break. Anyway, The RE also said we could first try ovarian drilling? Please tell me what the hell that is? I’m not an infertility expert but I read books and this newsgroup but never heard of such a thing. Is it safe, sure doesn’t sound it. And will my chances be better? He also said to do a lap. I guess he wants a human guinea pig!! I’ve seriously considered going to another RE. Any help is always appreciated.